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Publications

1. Shin, J. W., Park, H. T., Choe, S. A., & Jeon, O. H. (2023). Association of senescence-Associated secretory phenotype proteins with ovarian reserve among middle-Aged/older women. Menopause, 30(10), 1053-1057.  https://doi.org/10.1097/GME.0000000000002238

2. Baek, J. Y., Jung, H. W., Kim, K. M., Kim, M., Park, C. Y., Lee, K. P., Lee, S. Y., Jang, I. Y., Jeon, O. H., & Lim, J. Y. (2023). Korean Working Group on Sarcopenia Guideline: Expert Consensus on Sarcopenia Screening and Diagnosis by the Korean Society of Sarcopenia, the Korean Society for Bone and Mineral Research, and the Korean Geriatrics Society. Annals of Geriatric Medicine and Research, 27(1), 9-21. https://doi.org/10.4235/agmr.23.0009

3. Lee, C. S., Jeon, O. H., Han, S. B., & Jang, K. M. (2023). Mesenchymal Stem Cells for Enhanced Healing of the Medial Collateral Ligament of the Knee Joint. Medicina (Lithuania), 59(4), [725]. https://doi.org/10.3390/medicina59040725

4. Chin, A. F., Han, J., Clement, C. C., Choi, Y., Zhang, H., Browne, M., Jeon, O. H., & Elisseeff, J. H. (2023). Senolytic treatment reduces oxidative protein stress in an aging male murine model of post-traumatic osteoarthritis. Aging Cell, 22(11), Article e13979. https://doi.org/10.1111/acel.13979

5. Park, J. G., Han, S. B., Lee, C. S., Jeon, O. H., & Jang, K. M. (2022). Anatomy, Biomechanics, and Reconstruction of the Anterolateral Ligament of the Knee Joint. Medicina (Lithuania), 58(6), [786]. https://doi.org/10.3390/medicina58060786

6. Park, J. G., Han, S. B., Rhim, H. C., Jeon, O. H., & Jang, K. M. (2022). Anatomy of the anterolateral ligament of the knee joint. World Journal of Clinical Cases, 10(21), 7215-7223. https://doi.org/10.12998/wjcc.v10.i21.7215

7. Lee, S. G., Kim, D., Lee, J. J., Lee, H. J., Moon, R. K., Lee, Y. J., Lee, S. J., Lee, O. H., Kim, C., Oh, J., Lee, C. J., Lee, Y. H., Park, S., Jeon, O. H., Choi, D., Hong, G. R., & Kim, J. S. (2022). Dapagliflozin attenuates diabetes-induced diastolic dysfunction and cardiac fibrosis by regulating SGK1 signaling. BMC Medicine, 20(1), [309]. https://doi.org/10.1186/s12916-022-02485-z

8. Lee, H. G., Roh, S., Kim, H. J., Kim, S., Hong, Y., Lee, G., & Jeon, O. H. (Accepted/In press). Nanoscale biophysical properties of small extracellular vesicles from senescent cells using atomic force microscopy, surface potential microscopy, and Raman spectroscopy. Nanoscale horizons. https://doi.org/10.1039/d2nh00220e

9. Shin, J. W., Lee, E., Han, S., Choe, S. A., & Jeon, O. H. (2022). Plasma Proteomic Signature of Cellular Senescence and Markers of Biological Aging among Postmenopausal Women. Rejuvenation Research, 25(3), 141-148. https://doi.org/10.1089/rej.2022.0024

10. Gil, T. H., Zheng, H., Lee, H. G., Shin, J. W., Hwang, S. W., Jang, K. M., & Jeon, O. H. (2022). Senolytic drugs relieve pain by reducing peripheral nociceptive signaling without modifying joint tissue damage in spontaneous osteoarthritis. Aging, 14(15), 6006-6027. https://doi.org/10.18632/aging.204204

11. Jeon, O. H., Mehdipour, M., Gil, T. H., Kang, M.H., Aguirre, N. W., Robinson, Z. R., Kato, C., Etienne, J., Lee, H. G., Alimirah, F., Walavalkar, V., Desprez, P. Y., Conboy, M. J., Campisi, J., & Conboy, I. M. (2022). Systemic induction of senescence in young mice after single heterochronic blood exchange. Nature Metabolism, 4(8), 995-1006. https://doi.org/10.1038/s42255-022-00609-6

12. Rhim, H. C., Jeon, O. H., Han, S. B., Bae, J. H., Suh, D. W., & Jang, K. M. (2021). Mesenchymal stem cells for enhancing biological healing after meniscal injuries. World Journal of Stem Cells, 13(8), 1005-1029. https://doi.org/10.4252/wjsc.v13.i8.1005

13.Mehdipour, M., Mehdipour, T., Skinner, C. M., Wong, N., Liu, C., Chen, C. C., Jeon, O. H., Zuo, Y., Conboy, M. J., & Conboy, I. M. (2021). Plasma dilution improves cognition and attenuates neuroinflammation in old mice. GeroScience, 43(1). https://doi.org/10.1007/s11357-020-00297-8

14. Lee, D., Wufuer, M., Kim, I., Choi, T. H., Kim, B. J., Jung, H. G., Jeon, B., Lee, G., Jeon, O. H., Chang, H., & Yoon, D. S. (2021). Sequential dual-drug delivery of BMP-2 and alendronate from hydroxyapatite-collagen scaffolds for enhanced bone regeneration. Scientific reports, 11(1), [746]. https://doi.org/10.1038/s41598-020-80608-3

15. Go, S., Kang, M., Kwon, S. P., Jung, M., Jeon, O. H., & Kim, B. S. (2021). The Senolytic Drug JQ1 Removes Senescent Cells via Ferroptosis. Tissue Engineering and Regenerative Medicine, 18(5), 841-850. https://doi.org/10.1007/s13770-021-00346-z

16. Lee, S. G., Lee, S. J., Lee, J. J., Kim, J. S., Lee, O. H., Kim, C. K., Kim, D., Lee, Y. H., Oh, J., Park, S., Jeon, O. H., Hong, S. J., Ahn, C. M., Kim, B. K., Ko, Y. G., Choi, D., Hong, M. K., & Jang, Y. (2020). Anti-inflammatory effect for atherosclerosis progression by sodium-glucose cotransporter 2 (SGLT-2) inhibitor in a normoglycemic rabbit model. Korean Circulation Journal, 50(5), 443-457. https://doi.org/10.4070/kcj.2019.0296

17. Basisty, N., Kale, A., Jeon, O. H., Kuehnemann, C., Payne, T., Rao, C., Holtz, A., Shah, S., Sharma, V., Ferrucci, L., Campisi, J., & Schilling, B. (2020). A proteomic atlas of senescence-associated secretomes for aging biomarker development. PLoS biology, 18(1), e3000599. https://doi.org/10.1371/journal.pbio.3000599

18. Kim, S., Jeon, O. H., & Jeon, Y. J. (2020). Extracellular RNA: Emerging roles in cancer cell communication and biomarkers. Cancer letters, 495, 33-40. https://doi.org/10.1016/j.canlet.2020.09.002

19. Faust, H. J., Zhang, H., Han, J., Wolf, M. T., Jeon, O. H., Sadtler, K., Peña, A. N., Chung, L., Maestas, D. R., Tam, A. J., Pardoll, D. M., Campisi, J., Housseau, F., Zhou, D., Bingham, C. O., & Elisseeff, J. H. (2020). IL-17 and immunologically induced senescence regulate response to injury in osteoarthritis. Journal of Clinical Investigation, 130(10), 5493-5507. https://doi.org/10.1172/JCI134091

20. Jeon, O. H., Wilson, D. R., Clement, C. C., Rathod, S., Cherry, C., Powell, B., Lee, Z., Khalil, A. M., Green, J. J., Campisi, J., Santambrogio, L., Witwer, K. W., & Elisseeff, J. H. (2019). Senescence cell–associated extracellular vesicles serve as osteoarthritis disease and therapeutic markers. JCI insight, 4(7), [e125019]. https://doi.org/10.1172/jci.insight.125019

21. Jeon, O. H., David, N., Campisi, J., & Elisseeff, J. H. (2018). Senescent cells and osteoarthritis: A painful connection. Journal of Clinical Investigation, 128(4), 1229-1237. https://doi.org/10.1172/JCI95147

22. Jeon, O. H., Kim, C., Laberge, R. M., Demaria, M., Rathod, S., Vasserot, A. P., Chung, J. W., Kim, D. H., Poon, Y., David, N., Baker, D. J., Van Deursen, J. M., Campisi, J., & Elisseeff, J. H. (2017). Local clearance of senescent cells attenuates the development of post-traumatic osteoarthritis and creates a pro-regenerative environment. Nature Medicine, 23(6), 775-781. https://doi.org/10.1038/nm.4324

23. Kim, C., Shores, L., Guo, Q., Aly, A., Jeon, O. H., Kim, D. H., Bernstein, N., Bhattacharya, R., Chae, J. J., Yarema, K. J., & Elisseeff, J. H. (2016). Electrospun Microfiber Scaffolds with Anti-Inflammatory Tributanoylated N-Acetyl-d-Glucosamine Promote Cartilage Regeneration. Tissue Engineering - Part A, 22(7-8), 689-697. https://doi.org/10.1089/ten.tea.2015.0469

24. Jeon, O. H., Panicker, L. M., Lu, Q., Chae, J. J., Feldman, R. A., & Elisseeff, J. H. (2016). Human iPSC-derived osteoblasts and osteoclasts together promote bone regeneration in 3D biomaterials. Scientific reports, 6, [26761]. https://doi.org/10.1038/srep26761

25. Kim, C., Jeon, O. H., Kim, D. H., Chae, J. J., Shores, L., Bernstein, N., Bhattacharya, R., Coburn, J. M., Yarema, K. J., & Elisseeff, J. H. (2016). Local delivery of a carbohydrate analog for reducing arthritic inflammation and rebuilding cartilage. Biomaterials, 83, 93-101. https://doi.org/10.1016/j.biomaterials.2015.12.029

26. Jeon, O. H., & Elisseeff, J. (2016). Orthopedic tissue regeneration: cells, scaffolds, and small molecules. Drug Delivery and Translational Research, 6(2), 105-120. https://doi.org/10.1007/s13346-015-0266-7

Patents

1. Laberge RM, Campisi J, Davalos A, Demaria M, David N, Vasserot AP, Kirkland LJ, Tchkonia T, Elisseeff JH, Kim C, Jeon OH, Zhu Y (2019), Therapy for removing senescent cells and treating senescence-associated diseases using an mdm2 inhibitor, US patent appl. 16508119

2. David N, Davalos A, Laberge RM, Campisi J, Demaria M, Vasserot AP, Kim C, Jeon OH, Elisseeff JH, Kirkland JL, Tchkonia T, Zhu Y (2018), Treatment of join pain, US patent. 10130628

3. Laberge RM, Campisi J, Davalos A, Demaria M, David N, Vasserot AP, Baker DJ, Childs GB, Kirkland LJ, Tchkonia T, Deursen JV, Zhu Y, Elisseeff JH, Kim C, Jeon OH, Zhu Y (2018), Treatment for osteoarthritis by intra-articular administration of a cis-imidazoline, US Patent. 9855266

4. Laberge RM, Campisi J, Davalos A,Demaria M, David N, Vasserot AP, Kirkland LJ, Tchkonia T, Deursen JV, Elisseeff JH, Kim C, Jeon OH, Zhu Y (2018), Treatment for osteoarthritis in a joint by administering a means for inhibiting MDM2, US patent. 9993472

5. Laberge RM, Campisi J, Davalos A,Demaria M, David N, Vasserot AP, Kirkland LJ, Tchkonia T, Zhu Y, Elisseeff JH, Kim C, Jeon OH (2017), Unit dose of a cis-imidazoline for treating an osteoarthritic joint by removing senescent cells, US patent. 9849128

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